DATE:

Friday, September 6, 2019

TIME:

3:30 PM

LOCATION:

GMCS-314

SPEAKER:

Parag Katira, Ph.D, Department of Mechanical Engineering, SDSU.

ABSTRACT:

Cancer is a disease rooted in genetic mutations that allow tumor cells to avoid normal
cell death, divide uncontrollably and modify their microenvironment to avoid being
targeted by natural immune system. Sadly, there is vast heterogeneity in the genetic
and epigenetic factors driving this cancerous behavior across cancer types, cancer
patients and even cells within the same tumor making targeted treatment difficult and
expensive. On the other hand, studies have recently identified certain key mechanical
signatures of cancer cells and tumor microenvironments that seem to be more universal
across tumors and even across cancer types. The question still remains if and how these
mechanical signatures of tumors may influence the overall process of tumor growth and
metastasis and can these be targeted to alter the outcome of the disease. In this talk,
I will present some of our work on using mechanics based computational models to understand
the role of mechanics during various stages of tumor growth and metastasis and the various
insights gained from these models.

HOST:

Antoni Luque, Department of Mathematics & Statistics

DOWNLOAD:

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