THE GLOBAL EVOLUTION AND ADAPTATION OF VIBRIO CHOLERAE ACROSS MULTIPLE NICHE DIMENSIONS.
TITLE:
THE GLOBAL EVOLUTION AND ADAPTATION OF VIBRIO CHOLERAE ACROSS MULTIPLE
NICHE DIMENSIONS.
DATE:
Friday, Jan 20th, 2012
TIME:
3:30 PM
LOCATION:
GMCS 214
SPEAKER:
Robert Edwards.
Computational Science Research Center.
San Diego State University.
ABSTRACT:
Cholera has been the scourge of nations for millennia, and we are
currently in the midst of the latest cholera epidemic. Following the
devastating earthquake in Haiti in 2010 an outbreak of cholera killed
over 5,000 people. Despite treatments and our understanding of the
disease, cholera continues to change and adapt over time. Using the
latest generation of DNA sequencing technology – based on
semiconductors – we have sequenced and analyzed genomes from cholera
isolates collected around the world and through the decades. This
provides a view of the mechanisms that cholera uses to cause disease,
and the methods by which it evolves over time. Our computational,
statistical, and bioinformatics analysis has shed new light on the
genes that are important for the spread of this disease through time
and space.
HOST:
Dr. Jose Castillo.
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