FROM NETWORKS THROUGH GENES TO MECHANISMS: YEAST CELL CYCLE AND HUMAN HYPERTENSION


TITLE:


FROM NETWORKS THROUGH GENES TO MECHANISMS: YEAST CELL CYCLE AND HUMAN HYPERTENSION


DATE:


Friday, October 16th, 2009


TIME:


3:30 PM


LOCATION:


GMCS 214


SPEAKER:


Animesh Ray,
Professor, Systems Biology,
Keck Graduate Institute


ABSTRACT:


The interaction networks of genes, proteins and RNA have emerged as a powerful metaphor for understanding the complexities of biological processes. As in the human society where the behavior of complex entities, such as of businesses, social or political groups, are governed by specialized human interaction networks, specialized networks of molecular interactions govern cell behavior. I will address the utility of ‘network-motivated’ thinking through two research activities in my laboratory. The first is the discovery of an unexpectedly rich network of novel genetic interactions that illuminate the evolutionary robustness of the genome. The second is a network-guided approach to the discovery of genes which might predispose individuals to hypertensive disorders.


HOST:


Jose Castillo


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