TITLE:

Atoms of Multistationarity in Chemical Reaction Networks

DATE:

Friday, March 7th, 2014

TIME:

3:30 PM

LOCATION:

GMCS 214

SPEAKER:

Dr. Badal Joshi. California State University San Marcos

ABSTRACT:

Abstract: Multistationarity is a prerequisite for a reaction network to act as a biochemical switch. Theoretical tools that help rule out multistationarity include the Jacobian criterion of Craciun and Feinberg. We present an algorithm for simplifying the Jacobian criterion, which results in a significantly reduced computation. Further, we provide results that are helpful in establishing multistationarity of certain networks. The key result is that if a multistationary network N is “embedded” in a larger network G then G is also multistationary. The partial ordering resulting from the embedding property yields minimal (with respect to number of chemical species and reactions) multistationary networks. We also provide results which identify the smallest such minimal networks.

HOST:

Dr. Jose Castillo

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